Loquat Leaf Extract with Corosolic Acid is a powerful natural supplement with various health benefits. Its active compounds, including corosolic acid, flavonoids, triterpenes, and phenolic compounds, contribute to its potential for blood sugar regulation, anti-inflammatory and Antioxidant effects, cardiovascular support, and more.Corosolic acid achieves its hypoglycemic effect by stimulating the transport of glucose and promoting the absorption and utilization of glucose by cells. The excitatory effect of corosolic acid on glucose transport is similar to that of insulin; therefore, corosolic acid is also known as phytoinsulin. The results of animal experiments show that corosolic acid has significant hypoglycemic effects on both normal rats and mice with hereditary diabetes. Clinical studies have found that the drug can regulate insulin and blood glucose levels in the body and has a significant weight loss tendency (0.908-1.816 Kg monthly average weight loss), which is slow and does not require dieting. Corosolic acid also has a variety of other biological activities, such as a significant inhibitory effect on TPA-induced inflammatory responses, with anti-inflammatory effects stronger than those of the commercially available anti-inflammatory drug indomethacin; it also has DNA polymerase inhibitory activity, and inhibits the growth of a variety of tumor cells.
Active Substances Contained and Specific Effects
1. Corosolic Acid:
Corosolic acid is the primary active compound in loquat leaf extract, known for its antidiabetic properties. It helps regulate blood sugar levels by enhancing glucose uptake into cells and improving insulin sensitivity. Corosolic acid may also have anti-inflammatory, antioxidant, and weight management effects.
2. Triterpenes:
Loquat leaves contain several triterpenes, including ursolic acid and maslinic acid, which have anti-inflammatory, antioxidant, and anticancer properties. These compounds help protect cells from oxidative stress, reduce inflammation, and may inhibit the growth of cancer cells.
3. Flavonoids:
Flavonoids in loquat leaf extract, such as quercetin and kaempferol, are powerful antioxidants that help reduce oxidative stress and inflammation. They also support cardiovascular health by improving blood vessel function and reducing the risk of atherosclerosis.
4. Phenolic Compounds:
Effect: Phenolic compounds, including chlorogenic acid and caffeic acid, contribute to the extract’s antioxidant properties. They help neutralize free radicals, reduce oxidative damage, and support overall health by protecting against chronic diseases.
5. Saponins:
Saponins are natural compounds with immune-boosting and anti-inflammatory properties. They may also have cholesterol-lowering effects by binding to bile acids in the intestine, which promotes the excretion of cholesterol from the body.
6. Vitamins and Minerals:
Loquat leaves contain vitamins and minerals, such as vitamin C, potassium, and calcium, which contribute to overall health by supporting the immune system, maintaining healthy blood pressure, and promoting bone health.
Specific Health Effects
1. Blood Sugar Regulation:
Corosolic acid is well-known for its ability to regulate blood sugar levels, making loquat leaf extract beneficial for individuals with diabetes or those at risk. It enhances glucose uptake into cells and improves insulin sensitivity, helping to maintain healthy blood sugar levels.
2. Anti-Inflammatory and Antioxidant Effects:
The triterpenes, flavonoids, and phenolic compounds in loquat leaf extract have potent anti-inflammatory and antioxidant properties. These compounds help reduce inflammation in the body, protect cells from oxidative stress, and support overall health by lowering the risk of chronic diseases.
3. Cardiovascular Health:
The flavonoids and triterpenes in loquat leaf extract support cardiovascular health by improving blood vessel function, reducing blood pressure, and lowering cholesterol levels. These effects help reduce the risk of heart disease and stroke.
4. Weight Management:
Corosolic acid may aid in weight management by improving insulin sensitivity and promoting glucose uptake, which can help regulate appetite and reduce fat accumulation.
5. Immune Support: The saponins and other immune-boosting compounds in loquat leaf extract support the immune system, helping the body fight off infections and illnesses.
6. Anti-Cancer Potential:
The triterpenes and flavonoids in loquat leaf extract have shown potential in inhibiting the growth of cancer cells and reducing the risk of certain types of cancer. These compounds may help prevent the initiation and progression of cancer through their antioxidant and anti-inflammatory effects.
7. Skin Health:
The antioxidant properties of loquat leaf extract may help protect the skin from damage caused by UV radiation and environmental stressors. It may also promote skin healing and reduce the appearance of wrinkles and other signs of aging.
