Danshen Extract Salvianolic Acid B is a bioactive compound extracted from the roots of the Danshen plant (Salvia miltiorrhiza), also known as Chinese red sage. Salvianolic Acid B (Sal B) is a type of polyphenolic compound that is particularly notable for its potent Antioxidant and therapeutic properties. Danshen has been used for centuries in traditional Chinese medicine to treat various cardiovascular and inflammatory conditions.Danshen Extract Salvianolic Acid B is a potent and versatile compound with a wide range of therapeutic applications. Its powerful antioxidant, anti-inflammatory, and cardiovascular benefits make it a valuable ingredient in Dietary Supplements and herbal medicine. Whether used to support heart health, cognitive function, or to protect against chronic diseases, Salvianolic Acid B is a notable extract with significant health-promoting properties.
Key Characteristics
Source: Derived from the dried roots of Salvia miltiorrhiza, a perennial plant native to China and Japan.
Form: Available in various forms such as powdered extract, capsules, or tinctures, standardized to contain specific concentrations of Salvianolic Acid B.
Chemical Structure: Salvianolic Acid B is a water-soluble polyphenolic acid with a complex structure that contributes to its diverse biological activities.
Active Properties of Salvianolic Acid B
1. Antioxidant Activity
Free Radical Scavenging: Salvianolic Acid B has powerful antioxidant properties that neutralize free radicals and protect cells from oxidative stress, which is a contributing factor in aging and various chronic diseases.
Lipid Peroxidation Inhibition: It prevents lipid peroxidation, a process where free radicals damage cell membranes, thereby protecting cells and tissues from oxidative damage.
2. Anti-inflammatory Effects
Cytokine Modulation: Salvianolic Acid B inhibits the production and activity of pro-inflammatory cytokines, reducing inflammation in tissues and organs. This makes it beneficial for managing inflammatory conditions like arthritis and cardiovascular diseases.
NF-κB Pathway Inhibition: It suppresses the NF-κB signaling pathway, a critical regulator of inflammation and immune responses, thereby mitigating inflammatory responses in the body.
3. Cardiovascular Benefits
Vasodilation: Salvianolic Acid B promotes the dilation of blood vessels, improving blood flow and reducing the strain on the heart. This helps in managing hypertension and enhancing overall cardiovascular health.
Anti-thrombotic: It reduces the risk of thrombosis (blood clots) by inhibiting platelet aggregation, which can prevent conditions like heart attacks and strokes.
Endothelial Function: Supports the health of the endothelial cells lining the blood vessels, enhancing vascular function and reducing the risk of atherosclerosis.
4. Neuroprotective Effects
Cognitive Support: Salvianolic Acid B protects neurons from oxidative stress and inflammation, potentially improving cognitive function and reducing the risk of neurodegenerative diseases like Alzheimer’s and Parkinson’s.
Stroke Recovery: It has been shown to support recovery after ischemic stroke by reducing brain injury and promoting neurogenesis (the growth of new neurons).
5. Anti-fibrotic Properties
Organ Protection: Salvianolic Acid B inhibits the formation of fibrotic tissue, which can occur in organs like the liver, lungs, and kidneys. This makes it beneficial in conditions like liver fibrosis and pulmonary fibrosis.
Collagen Regulation: It modulates the production and deposition of collagen, a protein that plays a crucial role in fibrosis and tissue repair.
6. Anti-cancer Potential
Tumor Growth Inhibition: Salvianolic Acid B has shown potential in inhibiting the growth and proliferation of various cancer cells in laboratory studies, including liver, lung, and breast cancers.
Apoptosis Induction: It promotes apoptosis (programmed cell death) in cancer cells, which is a critical mechanism in preventing cancer progression.
Applications of Danshen Extract Salvianolic Acid B
1. Cardiovascular Health Supplements:
Heart Health: Used in dietary supplements aimed at improving heart health, managing blood pressure, and enhancing circulation.
Cholesterol Management: Helps in reducing LDL (bad) cholesterol levels and preventing atherosclerosis.
2. Anti-inflammatory and Antioxidant Formulations:
Joint Health: Incorporated into supplements for joint health and inflammation management, particularly beneficial for conditions like arthritis.
General Antioxidant: Included in antioxidant blends to provide broad-spectrum protection against oxidative stress and inflammation.
3. Neuroprotective Supplements:
Cognitive Function: Used in supplements designed to support brain health, improve memory, and reduce the risk of neurodegenerative diseases.
Stroke Recovery: Formulated into products aimed at supporting neurological recovery post-stroke.
4. Liver and Organ Health:
Liver Protection: Added to supplements for liver health to protect against liver damage and fibrosis.
Organ Support: Used in formulations that support the health and function of other organs, including the kidneys and lungs.
5. Anti-cancer Research:
Cancer Prevention and Treatment: Investigated in cancer research for its potential to inhibit tumor growth and promote cancer cell apoptosis.
6. Traditional Medicine:
Herbal Remedies: Continues to be used in traditional Chinese medicine formulations for its broad therapeutic effects, particularly in managing cardiovascular and inflammatory conditions.
