Celery Seed Extract Apigenin is a concentrated extract derived from the seeds of the celery plant (Apium graveolens), specifically enriched with apigenin, a bioactive flavonoid. Apigenin is one of the most abundant flavonoids in celery and is known for its potent Antioxidant, anti-inflammatory, and anti-cancer properties. This extract is often used in Dietary Supplements for its potential health benefits.Celery Seed Extract Apigenin is a concentrated source of apigenin, a powerful flavonoid with multiple health benefits. It is known for its anti-inflammatory, antioxidant, and potential anti-cancer properties, as well as its support for cardiovascular and neuroprotective health. This extract is used in dietary supplements to promote overall well-being, particularly in managing inflammation, supporting heart health, and potentially reducing the risk of chronic diseases.
Main Component
1. Apigenin:
Apigenin is the primary active compound in Celery Seed Extract. It is a flavonoid with strong antioxidant properties that help neutralize free radicals, reducing oxidative stress and lowering the risk of chronic diseases. Apigenin also exhibits anti-inflammatory effects by inhibiting the production of pro-inflammatory cytokines and enzymes. Furthermore, it has been shown to induce apoptosis (programmed cell death) in cancer cells, making it a potential anti-cancer agent. Apigenin may also promote relaxation and reduce anxiety by modulating neurotransmitter activity in the brain.
2. Luteolin:
Luteolin is another flavonoid found in celery seeds, though in lower concentrations than apigenin. It shares many of the same properties as apigenin, including antioxidant and anti-inflammatory effects. Luteolin has been studied for its neuroprotective benefits, as it may help prevent cognitive decline and protect against neurodegenerative diseases by reducing brain inflammation.
3. Phthalides (e.g., 3-n-butylphthalide):
Phthalides are aromatic compounds that contribute to the distinctive smell of celery seeds. 3-n-butylphthalide, a specific phthalide, is known for its cardiovascular benefits, including the ability to lower blood pressure by relaxing the smooth muscles in blood vessels, thereby improving circulation. It may also have neuroprotective effects, potentially aiding in the prevention of stroke and cognitive decline.
4. Vitamins and Minerals:
Although the focus of Celery Seed Extract is primarily on apigenin, the extract may also contain trace amounts of vitamins and minerals found in celery seeds, such as Vitamin K, magnesium, and calcium. These nutrients contribute to bone health, muscle function, and overall cardiovascular health.
Specific Health Effects
1. Anti-Inflammatory and Antioxidant Effects:
Apigenin and luteolin in Celery Seed Extract are powerful antioxidants that help protect cells from oxidative damage and reduce inflammation. These properties are beneficial for managing chronic inflammatory conditions, such as arthritis, and may lower the risk of chronic diseases, including heart disease and cancer.
2. Cardiovascular Health:
The phthalides in Celery Seed Extract, particularly 3-n-butylphthalide, support cardiovascular health by lowering blood pressure and improving blood flow. This helps reduce the risk of hypertension, stroke, and other cardiovascular conditions.
3. Cancer Prevention:
Apigenin has shown promise in preclinical studies as an anti-cancer agent. It can induce apoptosis in cancer cells, inhibit tumor growth, and prevent the spread of cancer cells.These effects make it a valuable compound for potential cancer prevention and therapy.
4. Neuroprotective Effects:
Apigenin and 3-n-butylphthalide may have neuroprotective benefits, helping to protect the brain from inflammation and oxidative stress. This can reduce the risk of neurodegenerative diseases such as Alzheimer's and Parkinson's disease and support cognitive health as one ages.
5. Anxiety and Mood Regulation:
Apigenin has been studied for its potential anxiolytic (anti-anxiety) effects. It may promote relaxation and reduce anxiety by interacting with certain receptors in the brain, such as the GABA receptors, which are involved in regulating mood and anxiety levels.
6. Digestive Health: While not as pronounced as in other celery-derived products, the fiber and other phytonutrients in Celery Seed Extract can contribute to digestive health by supporting regular bowel movements and maintaining a healthy gut microbiome.
