Sophora Flavescens Root Extract, commonly known as Matrine, is derived from the roots of the Sophora flavescens plant, a traditional Chinese medicinal herb. The plant is also known as "Ku Shen" in Chinese medicine and is used for its wide range of therapeutic properties. Matrine is one of the primary bioactive alkaloids found in the root, and it is valued for its potent anti-inflammatory, antiviral, and anticancer effects.Sophora Flavescens Root Extract Matrine is a powerful Herbal Extract with a range of therapeutic benefits. The active substances, including matrine, oxymatrine, sophoraflavanone G, kurarinone, and sophocarpine, contribute to its anti-inflammatory, antiviral, anticancer, and neuroprotective effects. This extract is widely used in traditional and modern medicine to treat various health conditions, including chronic inflammation, viral infections, cancer, liver disease, and neurological disorders.
Main Component
1. Matrine:
Matrine is the key bioactive alkaloid in Sophora flavescens and is known for its anti-inflammatory, antiviral, and anticancer properties. It has been studied for its ability to inhibit tumor growth, induce apoptosis (programmed cell death) in cancer cells, and modulate the immune response. Matrine also shows potential in treating hepatitis and other viral infections.
2. Oxymatrine:
Oxymatrine, another major alkaloid in Sophora flavescens, is closely related to matrine and shares many of its therapeutic effects. It is particularly noted for its antiviral properties, making it useful in treating hepatitis B and C, as well as other viral infections. Oxymatrine also exhibits anti-inflammatory effects and has been studied for its potential in treating autoimmune diseases.
3. Sophoraflavanone G:
This flavonoid found in Sophora flavescens contributes to its antimicrobial and anti-inflammatory properties. Sophoraflavanone G has been shown to have potent antibacterial activity, particularly against methicillin-resistant Staphylococcus aureus (MRSA), a challenging pathogen to treat.
4. Kurarinone:
Kurarinone is another flavonoid in the root extract that exhibits anti-inflammatory, anticancer, and hepatoprotective properties. It is known to inhibit the proliferation of cancer cells and protect the liver from damage caused by toxins or infections.
5. Sophocarpine:
Sophocarpine, an alkaloid found in the extract, has been studied for its neuroprotective and anti-inflammatory effects. It shows promise in protecting nerve cells from damage and reducing inflammation in neurological disorders.
Specific Health Effects
1. Anti-Inflammatory Properties:
Matrine and oxymatrine are highly effective in reducing inflammation in the body, making the extract useful in managing conditions like rheumatoid arthritis, inflammatory bowel disease, and other inflammatory disorders.
2. Anticancer Effects:
Matrine has been extensively studied for its anticancer properties. It inhibits the growth of various cancer cells, including those in liver, lung, breast, and prostate cancers. Matrine promotes apoptosis (programmed cell death) in cancer cells, thereby reducing tumor size and spread.
3. Antiviral Activity:
Oxymatrine, along with matrine, shows significant antiviral activity against hepatitis B and C viruses. It helps reduce viral load and liver inflammation, making it beneficial in the management of chronic hepatitis infections. It may also be effective against other viral infections.
4. immune system Modulation:
Matrine has immunomodulatory effects, which means it can help regulate the immune system. It enhances the body's ability to fight infections while also reducing overactive immune responses in autoimmune diseases.
5. Antibacterial and Antifungal Properties:
The presence of flavonoids like sophoraflavanone G in the extract contributes to its antimicrobial properties. It is effective against various bacterial and fungal pathogens, making it useful in treating infections, especially those resistant to conventional antibiotics.
6. Hepatoprotective Effects:
Kurarinone and other compounds in Sophora flavescens root extract help protect the liver from damage caused by toxins, infections, and oxidative stress. This makes the extract valuable in supporting liver health and treating liver-related conditions.
7. Neuroprotective Effects:
Sophocarpine has shown potential in protecting nerve cells from damage, which could be beneficial in treating neurological conditions such as Alzheimer's disease, Parkinson's disease, and other neurodegenerative disorders.
