Introduction to kaempferol products
Flavone is a kind of natural polyphenolic compounds, which exists in large quantities in fruits and vegetables. It has various biological activities such as Antioxidant, anticancer and anti-inflammatory, and has been the focus of research at home and abroad. kaempferol is a kind of flavonoid compound, also known as kaempfer-3, Kaempferol, Kaempferol flavonol, and thymol IChemicalbookII, which is widely found in natural plants such as fruits, vegetables and Chinese herbal medicine. Kaempferol has antioxidant, anti-inflammatory, anti-cancer, prevention and treatment of diabetes, atherosclerosis and osteoporosis, as well as protection of nerves, liver and myocardium, inhibition of protein kinase and other nutritional health effects. Kaempferol as a health food, medicine, has a very broad market.Kaverol is extracted from the dried and ripe fruits of Sophora Japonica L., a leguminous plant. The quality of raw materials and the whole process of production are strictly controlled by the company, and the raw materials meet the standards of pharmacopoeia.[Product name] kaempferol[Product alias] kaempferol, kaempferol, tetrahydroflavonol, kaempferol -3[English name] : Kaempferol[Product specification] : 30%~98%[Product properties] : yellow fine powder[Extraction source] : The fruit of the horn of the locust[Detection method] : High performance liquid phase (HPLC)Ethanol/water[ CAS No. ]520-18-3[ Subtype ]C15H10O6[ component quantity ]286.23[ Physical Properties ] Melting point 276℃-278℃ kaempferol is slightly soluble in water, soluble in hot ethanol, ether and alkali[Product size] 100% over 80 mesh[Recommended addition amount]1. The amount of propolis added is 0.12%-0.2%2. Recommended dosage of health care products: 15mg Kaempferol Function
1. Fight cancer
Kaempol plays an anticancer role by regulating the transcription of cyclooxygenase-2, inhibiting the function and expression of P-glycoprotein, inhibiting the anti-cell proliferation of interleukin-4, inducing cell apoptosis, interfering with cell signal transduction, enhancing the activity of tumor suppressor genes and inhibiting the expression of cancer genes and so on. Among them, it inhibits tumor cell proliferation by inducing tumor cell apoptosis.
2. Antioxidant
Naphthol can inhibit the formation of Advanced glycation endproducts and eliminate free radicals. It also has a strong antioxidant effect on the prevention of oxidative damage of intracellular lipids and DNA. It can also regulate the levels of NO and NOS and protect endothelial cells against oxidative damage by inhibiting the degradation of NO.
3. Anti-fertility and anti-osteoporosis
Kaempferol has obvious antifertility effect on animals, and shows estrogen-like activity. Estrogen can directly promote the proliferation of osteoblasts and promote the differentiation of osteoblasts after proliferation. Therefore, it is used to prevent and treat osteoporosis in clinic.
4. Hypoglycemic effect
Kaempferol can improve diabetic endothelial dysfunction, enhance the ability of microvascular cavity formation, effectively prevent type 2 diabetic cardiomyopathy and diabetic blood vessels, and is expected to become a new generation of insulin sensitizer.
5 Antibacterial, yellow staphylococcus and pseudomonas aeruginosa, typhoid bacillus, dysentery bacillus have inhibitory effect.
6. Relieve cough and treat bronchitis.
7. Inhibition of aldose reductase is beneficial to the treatment of diabetic cataract
8. With mutagen activity, when the concentration is 1×10-4mol/L, it can inhibit lymphocyte proliferation.
9. Antiepileptic, anti-inflammatory, spasmolytic, anti-ulcer, cholelitic diuretic.
Kaempferol Application
Application and application prospect: At present, the anticancer effect of flavonols has become a hot topic in the research and development of pharmaceutical workers all over the world. Kaempferol, which has similar chemical structure with quercetin, has high medicinal value in anticancer, antioxidant, anti-fertility, anti-osteoporosis, hypoglycemia and other aspects, and has been clinically used in the treatment of gastric cancer and cardiovascular and cerebrovascular diseases. In recent years, with the continuous improvement of the experimental level, many valuable clues have been found. Based on the research results of the pharmacological effects of kaolin, its wide application in clinic will become the focus of future research, and also lay a foundation for expanding its application in food, health food and medicine.
Case one: swisse propolis
The swisse propolis contains kaempferol and quercetin, which are also great anti-fungal agents.
Case two: sea-buckthorn flavonoids
The main active components are low glucoside containing isorhamnetin, isorhamnetin - 3-b-D-glucoside, isorhamnetin - 3-b-rutin, quercetin and kaempferol
Function: cough and expectorant, digestion and stagnation, promoting blood circulation and dispersing blood stasis.
Kaempferol product Advantages
1. Our company has been focusing on the production of Robinia pseudoacacia extract for decades, and has controlled the quality and stability of raw materials from the source. From the entry of raw materials to the final products, we strictly follow the GMP requirements for control, to ensure product quality.2. The company has advanced imported testing equipment to ensure the traceability testing of every link from raw materials to production.3. Professional technical team, strict control of quality and quality.4. No pesticide residue, low solvent residue, high purity.
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