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Fenugreek Galactomannan and Its Versatile Applications

2024-11-01

Shaanxi Zhongyi Kangjian Biotechnology Co ., Ltd . is a high - tech enterprise specializing in the research , development , production and sales of plant extracts , natural Fruit And Vegetable Powder , health food raw materials , etc . The company is headquartered in Xi ' an National high - medicine technology innovation and development for more than 10 years . With rich experience in identification , research , development and production of active ingredients of Chinese medicinal plants , we focus on providing raw material supply and one - stop product solutions for customers in food and beverage , health food , cosmetics and other industries at home and abroad .

Fenugreek extract

Fenugreek is a medicinal plant with a long history. Its pods and leaves are often used as medicine and, in Indian culture, as seasoning.
Its origin is widely debated. It was suggested in 1926 that it was originally cultivated in the Mediterranean region, but later it was said that it originated in Asia. It is also said to be native to the Mediterranean, Southern Europe, and Western Asia.
But in terms of the history of use, its application history is also very long, since 1000 BC in the Indian traditional medicine literature appeared. Later, in 65 AD, the Greek physician Dioscorides also mentioned fenugreek in his work.
In addition to medicinal use, fenugreek has many uses in food. Fenugreek seeds are eaten in curries in India and are also used as a coffee substitute.
In Africa, it is used as an herbal tea, and it is also eaten directly after the seeds are germinated. Moroccans also saute it with chicken and lentils. Especially because according to Moroccan tradition, fenugreek can promote the production of breast milk, so breastfeeding women will eat fenugreek.

Fenugreek

Basic information of fenugreek extract

Product name: Fenugreek extract
Specification: 10:1, fenugreek saponin 50%
Detection method :HPLC
Properties: Brown powder
Active Ingredients: It contains trigonellinelline, diosgenin-B-D-blucoside, vitexin, saponaretin, isoorientin, vitexin and vitexin. vitexin-7-glucoside), trigonellusin Ⅰ, (vicenin Ⅰ,).

Fenugreek

Pharmacological effects of fenugreek extract

1. Blood pressure lowering effect 4-hydroxyisoleucine is isolated from fenugreek, which has therapeutic effect on type 2 diabetes. Fenugreek has the effects of supplemening Yang, lowering blood sugar and lowering blood lipids, which may be related to the above amino acids.
2. Fenugreek extract can reduce the content of urea nitrogen and creatinine in serum of rats with renal failure. Fenugreek decoction is effective in treating chronic renal failure.
3. Trigonelline has hypoglycemic activity in normal animals and chemically induced diabetic animals; The Saponins in the extract of defatted fenugreek seed have the effect of lowering blood sugar. Galactomannan contained in fenugreek extract has significant effects on lowering blood sugar, regulating blood lipids and reducing weight.
4. Prevention and treatment of fatty liver fenugreek total saponins (TFGs) can significantly reduce serum TG,TC and LDL levels in rat fatty liver model. In addition, liver index, TG,TC,MDA,FFA and HYP contents and GST activity significantly increased the activities of SOD,NO,Na+-K+ -ATPase and Ca2+-Mg2+ -ATPase in liver, significantly reduced the extent and range of lipid drop distribution in hepatocyte plasma, and significantly inhibited the expression of hepatocyte cytochromic P450ⅡE1 .
5. Anti-ulcer effect Fenugreek seed water extract and the gel part isolated from the seed have obvious anti-ulcer activity. This effect is not only due to its inhibition of gastric acid secretion, but also has a certain effect on gastric mucosal glycoprotein. The water extract of fenugreek seed can prevent oil peroxidation caused by alcohol by improving the Antioxidant capacity of gastric mucosa, thus reducing mucosal damage.

6. Anti-tumor effect The papainine contained in fenugreek seeds has significant activity against lymphoid leukemia. The trigonelline contained in the seed can prolong the life of leukemia P388 mice by 31% at the level of 12.5mg·kg-1, and has obvious inhibitory effect on mouse liver cancer (HAc). Way of the water extract of fenugreek seeds by subcutaneous injection of vaccination Ehrlich ascites carcinoma (EAC) Ehrlichascitescarcinoma, before and after vaccination in mice, the results of cancer cell growth inhibition rate of more than 70%. The number of cells and macrophages in mice peritoneal effluents (Chemicalbook secretion) was increased.
7. Protective effect on acute and chronic chemical liver injury Fenugreek extract can effectively inhibit the elevation of serum ALT and AST in mice with acute liver injury, showing a good dose-response relationship. Fenugreek water extract has a protective effect on the liver of rats with CTC induced chronic liver injury. The mechanism of its protective effect on acute and chronic chemical liver injury of mice and rats may be lipid peroxidation and increase of GSH-Px enzyme activity.

8. The methanol extract of defatted part of fenugreek seed can significantly reduce the serum cholesterol level of normal dogs. The total extract also reduced the serum total cholesterol of diabetic hyperlipidemia dogs. Trigonelline contained in fenugreek seeds can reduce the content of total cholesterol and free cholesterol in mouse plasma.

9. Protective effect of fenugreek total saponins on cerebral ischemia significantly prolonged mean survival and craniotomy wheeting time of mice with acute incomplete cerebral ischemia, suggesting that fenugreek has protective effect on cerebral ischemic injury. Fenugreek total saponins can prolong the blood coagulation time of mice, inhibit the platelet aggregation rate of rabbits, reduce blood viscosity, and improve blood flow and microcirculation.
10. The material basis of tonifying kidney and strengthening Yang of fenugreek is the high content of zinc and manganese in seeds. According to research, the content of zinc and manganese in kidney tonifying Chinese medicine is high, if the lack of zinc and manganese in the body will cause low endocrine function and atrophy of glands, reduce endocrine hormones, slow growth, gonadal degeneration, sexual dysfunction.
11. Improve learning and memory disorders Fenugreek contains effective ingredients to promote protein synthesis, which has the effect of improving learning and memory disorders. Lecithin, one of the effective ingredients contained in fenugreek seeds, can improve nerve dysfunction and disorder, restore brain function, enhance memory and anti-aging.
12. Studies on antioxidant effects found that after fenugreek was added to the diet of alloxacil-induced diabetic rats, lipid peroxidation was alleviated, the contents of glutathione and beta-carotene in blood were significantly increased, and the content of vitamin E was decreased.
13. Anti-inflammatory, weight loss fenugreek seeds contain steroid saponins have diuretic, anti-inflammatory and other activities. Long-term use of fenugreek gum (mixed with various foods after consumption) has a better weight loss function for obesity.

Fenugreek extract

Conclusion

In this era, women's health has become an indisputable focus, especially many menopausal women around the world do experience some health and emotional problems. And how to solve it in a pure natural way is one of the topics that the market has been studying, perhaps fenugreek is a raw material that can solve this problem.

Fenugreek extract.

The above is about fenugreek extractrelated information.In addition, except to the fenugreek extract, we also have other products related to herbal extracts. Examples include fruit and vegetable powders, standardized extracts, mushroom extracts, natural Plant Pigments, weight loss extracts and Dietary Supplements. Shaanxi Zhongyi Kangjian  Biotechnology Co., Ltd. has established a direct collection system of plant raw materials to ensure the high quality of original medicinal materials. If you are interested in our products, please contact us.

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